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With our proprietary technology platform, we are developing targeted nanobindis with precise bimolecular properties optimized to deliver therapeutic and imaging agents for specific detection and therapeutic applications. This technology concentrates the drug and imaging agent at the intended site of action while eliminating or minimizing systemic exposure, thereby improving efficacy and reducing off-target and often cytotoxic side effects.  In order to deliver these important clinical benefits, the targeted nanobindis need to be optimized across a set of biomolecular properties in order to:

Evade the host immune system

• Bind preferentially to the target sites
• Accumulate in the target tissue
• Provide the desired drug release profile
• Provide imaging capabilities for knowledge based decision support system
• Provide capability to monitor the clinical relevance of the treatment

Our innovative target specific delivery platform provides the unique capability to generate targeted nanobindi libraries with distinct functional properties, screen for delivery vehicles with the optimal characteristics for the application, and reproducibly manufacture delivery vehicles with those precise properties. Chikujee's functionally optimized delivery vehicles are designed to capitalize on providing finer control for cell specific imaging and binding:

• Cell Specific Imaging Chikujee's delivery vehicles concentrate in areas of diseased tissue. The MRI contrasting agents embedded in the core of nanobindis besides ultrasensitive detection of disease tissue allow in vivo localization of delivery vehicles within the target cells.
• Cell specific targeting - Chikujee's delivery vehicles are designed to bind with high specificity and avidity to targeted cell-surface proteins or extracellular matrix components. The specificity is dependent on the specificity of targeting molecule and can be fine tuned by the selection of one or more targeting molecules.

The multifunctional nanobindi technology developed by the company addresses two of the most critical unmet needs of the drug development. The multi functional nanobindis provide the ability to deliver and monitor targeted therapeutics and imaging agents to the diseased cells without common side effects. The combined ability to deliver the drugs and monitor its efficacy at the site of action provide unique market advantages in this competitive market place. 

We have clearly defined the target market and have differentiated ourselves by offering unique and leading edge solutions that are mission-critical to our customers unmet needs.